The single viral genome takes the virus in culture or natural samples as the research object, first isolates a single viral particle and performs whole genome amplification, obtains genome sequence information to identify the virus, and configures the corresponding analysis process according to the reference genome of the target virus.

Whole-genome sequencing analysis of viruses will greatly facilitate the identification of emerging infectious diseases, the development of rapid detection reagents, the development of vaccines and drugs, and the estimation of transmission routes. In addition, it is important to improve our understanding of viral diversity, adaptability, ecological properties, and evolution.