From a biological point of view, the mRNA level represents the intermediate state of gene expression, and the potential expression of protein can be speculated, and protein is the direct executor of life function, which has a direct and important role in the measurement of gene expression level. In this way, we can interpret the law and essence of life activities at different omics levels, explain biological problems as a whole, comprehensively explore the disease mechanism and stress mechanism of organisms, and accurately study the expression patterns and regulatory mechanisms of important genes.
Joint analytics benefits
l Transcriptome and proteomics data complement each other, allowing for all-round analysis of mRNA and protein expression levels in organisms in specific states;
l Through in-depth analysis of data, we can dig out differential genes or differential proteins, and find and verify some important regulatory pathways;
l For those species with lack of protein database or incomplete annotation, constructing a protein search library from transcriptome data can greatly improve the number and quality of protein identification.